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gltS gltS hutG-2 hutG-2 hexR hexR PA5073 PA5073 gltR gltR PA1256 PA1256 eda eda PA1339 PA1339 PA1260 PA1260 PA5076 PA5076 PA1257 PA1257
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
gltSGlutamate/sodium ion symporter, GltS; Catalyzes the sodium-dependent transport of glutamate. Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family. (404 aa)    
Predicted Functional Partners:
hutG-2
Probable arginase family protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family.
  
  
 0.900
hexR
Probable transcriptional regulator; Involved in regulation of glucose metabolism. Transcriptional repressor of the gap-1 gene and of the edd-glk-gltR-2 and zwf-pgl-eda operons. Acts by binding directly to an inverted pseudopalindromic sequence in the promoter region.
   
  
 0.884
PA5073
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences); Belongs to the UPF0158 family.
   
  
 0.781
gltR
Two-component response regulator GltR; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
      
 0.765
PA1256
Amino acid ABC transporter ATP binding protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.762
eda
2-keto-3-deoxy-6-phosphogluconate aldolase; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the KHG/KDPG aldolase family.
      
 0.717
PA1339
Amino acid ABC transporter ATP binding protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.710
PA1260
Amino acid ABC transporter periplasmic binding protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
      
 0.706
PA5076
Probable binding protein component of ABC transporter; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the bacterial solute-binding protein 3 family.
      
 0.703
PA1257
Amino acid ABC transporter membrane protein; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
   
  
 0.701
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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